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INHIBITORS OF CANINE JANUS KINASE AND USES THEREOF

Application US20260092070A1 Kind: A1 Apr 02, 2026

Inventors

Andrew Antony CALABRESE, David T. STANTON

Abstract

Provided herein are compounds having inhibitory activity toward the Janus Kinase 1 (JAK-1) enzyme, and which are useful as therapeutic and/or prophylactic agents. The compounds may be useful in treating inflammatory disorders in non-human mammals, for example, in treating canine atopic dermatitis. Also provided herein are methods for preparation of such compounds.

CPC Classifications

C07D 487/04 A61K 31/519 A61K 31/5377 A61K 31/635 A61P 17/04 A61P 29/00

Filing Date

2025-12-02

Application No.

19405620