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CRYSTALLINE SALT FORMS OF N-((1-(2-(TERT-BUTYLAMINO)-2-OXOETHYL)PIPERIDIN-4-YL) METHYL)-3-CHLORO-5-FLUOROBENZAMIDE AND METHODS OF USE THEREOF

Application US20260092037A1 Kind: A1 Apr 02, 2026

Inventors

David T. Jonaitis, Lisa McCracken

Abstract

Described herein, in part, are crystalline and salt forms of N-((1-(2-(tert-butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide useful for preventing and/or treating a disease or condition relating to aberrant function of a T-type calcium channel, such as epilepsy and epilepsy syndromes (e.g., absence seizures, juvenile myoclonic epilepsy, or a genetic epilepsy), tremor (e.g., essential tremor), and psychiatric disorder (e.g., mood disorders (e.g., major depressive disorder)).

CPC Classifications

C07D 211/26 A61K 31/445 C07C 55/07 C07C 55/08 C07C 55/12 C07C 55/14 C07C 55/20 C07C 57/145 C07C 57/15 C07C 65/11 C07C 307/02 C07C 309/04 C07C 309/05 C07C 309/29 C07C 309/35 C07D 239/557 C07B 2200/13

Filing Date

2025-08-27

Application No.

19311876