CRYSTALLINE SALT FORMS OF N-((1-(2-(TERT-BUTYLAMINO)-2-OXOETHYL)PIPERIDIN-4-YL) METHYL)-3-CHLORO-5-FLUOROBENZAMIDE AND METHODS OF USE THEREOF
Application
US20260092037A1
Kind: A1
Apr 02, 2026
Inventors
David T. Jonaitis, Lisa McCracken
Abstract
Described herein, in part, are crystalline and salt forms of N-((1-(2-(tert-butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide useful for preventing and/or treating a disease or condition relating to aberrant function of a T-type calcium channel, such as epilepsy and epilepsy syndromes (e.g., absence seizures, juvenile myoclonic epilepsy, or a genetic epilepsy), tremor (e.g., essential tremor), and psychiatric disorder (e.g., mood disorders (e.g., major depressive disorder)).
CPC Classifications
C07D 211/26
A61K 31/445
C07C 55/07
C07C 55/08
C07C 55/12
C07C 55/14
C07C 55/20
C07C 57/145
C07C 57/15
C07C 65/11
C07C 307/02
C07C 309/04
C07C 309/05
C07C 309/29
C07C 309/35
C07D 239/557
C07B 2200/13
Filing Date
2025-08-27
Application No.
19311876