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CRYSTALLINE SALTS OF A T-TYPE CALCIUM CHANNEL MODULATOR AND METHODS OF USE THEREOF

Application US20260092036A1 Kind: A1 Apr 02, 2026

Inventors

Daniel Thomas Walters, Thomas San Ie

Abstract

The present disclosure provides Pattern D, i.e., a crystalline form of N-((1-(2-(tert-butylamino)-2-oxoethyl)piperidin-4-yl)methyl)-3-chloro-5-fluorobenzamide hydrochloride salt trihydrate (Compound 1). The present disclosure also provides pharmaceutical compositions comprising Compound 1 in the form of Pattern D, as well as methods of treating neurological and psychiatric disorders by administering to a subject in need thereof Compound 1 in the form of Pattern D or a pharmaceutical composition comprising Compound 1 in the form of Pattern D.

CPC Classifications

C07D 211/26 A61K 31/445 A61K 47/38

Filing Date

2025-08-27

Application No.

19311030