Recombinant Fc domain - IL2 variant polypeptides and combination therapy with membrane-anchored antigen binding polypeptides
Application
US20260091062A1
Kind: A1
Apr 02, 2026
Assignee
Hoffmann-La Roche Inc.
Inventors
Diana DAROWSKI, Stephan GASSER, Christian KLEIN, Simone LANG, Dario VENETZ
Abstract
The present invention relates to the combination therapy of recombinant Fc domain-IL-2 variant polypeptides with membrane-anchored antigen binding polypeptides in the prevention or treatment of cancer.
CPC Classifications
A61K 35/17
A61K 40/11
A61K 40/31
A61K 40/4217
A61K 40/4234
A61P 35/00
A61P 37/04
C07K 14/55
C07K 14/7051
C07K 14/70517
C07K 14/70535
C07K 14/7155
C12N 5/0018
A61K 2239/11
C07K 2319/30
C12N 2501/2302
C12N 2501/515
Filing Date
2025-07-17
Application No.
19272092