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APPLICATION OF CARBASALATE CALCIUM IN PREPARING DRUG FOR TREATMENT OF HYDROCEPHALUS

Application US20260091044A1 Kind: A1 Apr 02, 2026

Assignee

Tianjin University

Inventors

Dong MING, Xiuyun LIU, Meijun PANG, Hui ZHI, Xiaosong GU, Xiaoguang TONG, Huijie YU, Wenyuan GAO, Ke PU, Zongwei CAI, Weijian ZONG

Abstract

An application of carbasalate calcium in preparing the drug for the treatment of hydrocephalus is provided, and the drug uses carbasalate calcium as the only or main active ingredient. The invention first discovered the effect of carbasalate calcium in the treatment of hydrocephalus, which can significantly reduce the area of the fourth ventricle of the zebrafish model of hydrocephalus, and significantly increase the swimming distance, swimming time, swimming speed, and rotational motion frequency of the zebrafish model of hydrocephalus; the experimental data provided by the invention show that carbasalate calcium has great application prospects in the treatment of hydrocephalus, and provides an effective candidate drug for alleviating the pain of hydrocephalus patients and reducing the risk and cost of treatment; it broadens the scope of action of carbasalate calcium.

CPC Classifications

A61K 31/616 A61K 31/17

Filing Date

2025-02-21

Application No.

19059317