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Methods of Treating Heavy Menstrual Bleeding

Application US20260091041A1 Kind: A1 Apr 02, 2026

Inventors

Kristof Chwalisz, Jane Castelli-Haley, Oscar Antunez Flores, Keith Gordon, Rita Jain, Juki Wing-Keung Ng, Janine D. North, Charlotte D. Owens, Hannah Palac, Paul M. Peloso, Michael C. Snabes, Ahmed M. Soliman, James W. Thomas, Mohamad Shebley

Abstract

The present invention relates to the method of treating heavy menstrual bleeding in a subject with or without uterine fibroids and in need of treatment by administering an effective amount of 4-((R)-2-[5-(2-fluoro-3-methoxy-phenyl)-3-(2-fluoro-6-trifluoromethyl-benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenyl-ethylamino)-butyric acid or a pharmaceutically acceptable salt thereof, in combination with estrogens and progestogens.

CPC Classifications

A61K 31/57 A61K 31/513 A61K 31/567 A61P 15/00

Filing Date

2025-08-15

Application No.

19301199