← USPTO Patent Applications

COMBINATION THERAPIES COMPRISING PANOBINOSTAT FOR THE TREATMENT OF CHOLANGIOCARCINOMA

Application US20260091021A1 Kind: A1 Apr 02, 2026

Inventors

Theresa AHRENS, Alexandra GADE, Eivind HOVIG, Jo KLAVENESS, Johannes LANDSKRON, Kjetil TASKEN, Tove Cecilie VIEBE

Abstract

The present invention relates to compositions and methods for treatment of cholangiocarcinoma and in particular to combination therapies comprising panobinostat compositions in combination with other cytotoxic agents, e.g. agents that potentiate the effects of panobinostat, for use in the treatment of cholangiocarcinoma. Pharmaceutical compositions comprising panobinostat and other cytotoxic agents are also provided.

CPC Classifications

A61K 31/4045 A61K 31/09 A61K 31/185 A61K 31/282 A61K 31/337 A61K 31/352 A61K 31/365 A61K 31/404 A61K 31/4545 A61K 31/4706 A61K 31/4745 A61K 31/506 A61K 31/517 A61K 31/519 A61K 31/5377 A61K 31/5517 A61K 31/704 A61K 33/243 A61P 35/00

Filing Date

2025-12-09

Application No.

19413668