ORAL MUCOSAL FORMULATIONS OF ASPIRIN

Abstract

Disclosed herein, in part, are pharmaceutical formulations for oral mucosal (e.g., sublingual and/or buccal) administration comprising micronized aspirin, (e.g., 91 mg to 200 mg micronized aspirin), a buffer, a surfactant, and one or more pharmaceutically acceptable excipients, wherein the pH of a solution of the formulation dissolved in 1 mL distilled water is less than or equal to 3. Methods of treating a subject in need thereof comprising administering one or more disclosed pharmaceutical formulations to the subject are also provided herein.

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