USE OF HOMEOBOX CONTAINING 1 (HMBOX1) INHIBITOR IN PREPARATION OF DRUG FOR PREVENTION AND/OR TREATMENT OF MUSCLE ATROPHY

Abstract

Use of a homeobox containing 1 (HMBOX1) inhibitor in preparation of a drug for prevention and/or treatment of muscle atrophy. Functional experiments at the cellular level show that inhibiting the expression of HMBOX1 may effectively suppress the occurrence of muscle atrophy. Furthermore, functional experiments at the animal level demonstrate that inhibiting HMBOX1 expression has preventive and therapeutic effects against muscle atrophy. Therefore, the HMBOX1 inhibitor is used for the prevention and/or treatment of muscle atrophy, offering a new approach for the development of drugs that inhibit muscle atrophy.

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