METHOD OF PURIFYING AND ISOLATING COLLAGENASE
Application
US20260085304A1
Kind: A1
Mar 26, 2026
Inventors
Christine A. Sheaffer, Michael Berbaum, John Hanna, Jason Dziadosz, Daniel Shanafelt
Abstract
The present invention relates to the fields of collagenase production and collagenase products, and particularly to improving the reproducibility, purity, and stability of collagenase I and collagenase II compositions, where the compositions are pure to at least 95% by area as measured by reverse phase high pressure liquid chromatography (RP-HPLC) and essentially free of neutral protease.
CPC Classifications
C12N 9/52
C12Y 304/24003
A61K 31/00
A61K 38/00
G01N 33/56911
Filing Date
2025-09-23
Application No.
19336963