GENETICALLY MODIFIED LIGNOCELLULOLYTIC CLOSTRIDIUM ACETOBUTYLICUM

Abstract

The present invention relates to a genetically modified Clostridium acetobutylicum able to grow on lignocellulosic biomass, in which the cip-cel operon is overexpressed, the expression level of each gene of the cip-cel operon in the genetically modified Clostridium acetobutylicum being higher than its expression level in a corresponding non-genetically modified Clostridium acetobutylicum, as well as derivatives thereof with further modifications increasing growth on lignocellulosic biomass, and the use of these strains for the production of bulk chemicals by conversion of lignocellulose as source of carbon, such as ethanol, butanol, glycerol, 1,2-propanediol, acetone, isopropanol, isobutene, hydrogen, acetic acid and lactic acid and the like.

CPC Classifications