BISPECIFIC ANTIBODY TO HUMAN TIM-3 AND HUMAN CD39, AND USE THEREOF
Application
US20260085127A1
Kind: A1
Mar 26, 2026
Inventors
Norihiro NAKAMURA, Kanto NAKAJIMA, Yuji MISHIMA, Noriko MATSUMOTO
Abstract
An antibody or antibody derivative having a higher immune checkpoint inhibitory effect. The antibody or antibody derivative is capable of enhancing immune activity against cancer cells, and can be used to treat cancer. The antibody is a heterodimeric antibody or antibody derivative capable of binding to both the TIM-3 and CD39 antigens. The heterodimeric antibody or antibody derivative is capable of enhancing immune activity against cancer cells.
CPC Classifications
C07K 16/2896
A61K 38/00
A61P 35/00
C07K 16/46
G01N 33/5011
C07K 2317/24
C07K 2317/31
C07K 2317/565
C07K 2317/622
C07K 2317/732
Filing Date
2023-04-07
Application No.
18854355