PEPTIDES THAT SELECTIVELY BIND TO Trop2 AND USE THEREOF
Assignee
KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
Inventors
Byung-Heon LEE, Uttapol PERMPOON, Peti Thuwajit
Abstract
The present disclosure relates to a peptide binding to Trop 2 and a use thereof, wherein, in an attempt to find a peptide having an ability of specifically binding to Trop 2, a peptide (amino acid sequence: CSTLNVESC (SEQ ID NO: 1)) that selectively binds to Trop 2 was discovered using a phage display technique. Targeting cancers that are highly resistant to anticancer drugs in breast cancer (in particular, triple-negative breast cancer), pancreatic cancer, and cholangiocarcinoma while having no effective treatments, an effective anticancer drug may be prepared by delivering cancer-specific drugs or developing targeted therapeutic agents using the peptide of the present disclosure.
CPC Classifications
Filing Date
2023-08-10
Application No.
19107750