METHOD FOR THE REDUCTION OF HOST CELL PROTEINS IN AFFINITY CHROMATOGRAPHY
Application
US20260085090A1
Kind: A1
Mar 26, 2026
Assignee
Genentech, Inc.
Inventors
Paul MCDONALD, Richard ST. JOHN, Marc Wong, Roberto FALKENSTEIN, Wolfgang KOEHNLEIN, Klaus SCHWENDNER, Bernhard SPENSBERGER, Michael WIEDMANN, Frank ZETTL, Annika KLEINJANS, Carina KOPP, Benjamin TRAN, Ryan ERICKSON
Abstract
The current invention reports a method for purifying an antibody by reducing the content of a host cell protein. The method employs a wash step with a low conductivity aqueous solution in an affinity chromatography.
CPC Classifications
C07K 1/22
C07K 16/18
C07K 16/22
C07K 16/2854
C07K 16/32
C07K 16/36
C07K 2317/14
C07K 2317/31
Filing Date
2025-12-02
Application No.
19406716