HETEROCYCLIC DERIVATIVES AS JANUS KINASE INHIBITORS
Application
US20260085077A1
Kind: A1
Mar 26, 2026
Assignee
CHIESI FARMACEUTICI S.P.A.
Inventors
Alessandro ACCETTA, Alberto CUZZOLIN, Fabio RANCATI, Andrea RIZZI, Ivaylo Jivkov ELENKOV, Milan MESIC, Ela RADOŠEVIC
Abstract
The present invention relates to a compounds of general formula (I) inhibiting the JAK family of non-receptor tyrosine protein kinases (JAK1, JAK2, JAK3, and TYK2); methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of the JAK family non-receptor kinases; in particular for the treatment of various inflammatory diseases including asthma, COPD and other respiratory diseases.
CPC Classifications
C07D 519/00
A61K 9/007
A61K 31/519
A61K 31/5377
A61K 31/538
A61K 31/541
A61K 31/5415
A61K 31/553
A61K 45/06
C07D 471/04
Filing Date
2023-09-08
Application No.
19109331