PYRAZOLYLCARBOXAMIDE COMPOUNDS AND THEIR USE IN THERAPY
Application
US20260085073A1
Kind: A1
Mar 26, 2026
Inventors
Kenneth G. Carson, Geraldine Cirillo Harriman, Arwel Lewis, Gabriele Fumagalli, Benjamin Paul Whittaker, Alison Jones, Robert Stuart Laurie Chapman, Maria Angel Palomero-Vazquez, Riccardo Guareschi, Christopher James Lock, James Henry Lewis, Antonio Dore, Alicia Jayne Carey
Abstract
The invention provides pyrazolylcarboxamide compounds, pharmaceutical compositions, their use for inhibiting mucosa-associated lymphoid tissue lymphoma translocation protein I (MALT1), and their use in the treatment of a disease or condition, such as a proliferative disorder, inflammatory disorder, or autoimmune disorder.
CPC Classifications
C07D 495/04
A61K 31/4155
A61K 31/4439
A61K 31/444
A61K 31/4545
A61K 31/4709
A61K 31/4725
A61K 31/4745
A61K 31/498
A61K 31/4985
A61K 31/502
A61K 31/5025
A61K 31/517
A61K 31/519
A61K 31/5365
A61K 31/538
A61K 31/5383
A61K 31/551
C07B 59/002
C07D 401/12
C07D 401/14
C07D 403/12
C07D 405/14
C07D 409/14
C07D 413/14
C07D 417/14
C07D 471/04
C07D 487/04
C07D 491/044
C07D 491/048
C07D 498/04
C07D 513/04
Filing Date
2023-09-12
Application No.
19110200