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LEUCINE RICH REPEAT KINASE 2 (LRRK2) DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE

Application US20260085066A1 Kind: A1 Mar 26, 2026

Inventors

Steven M. Sparks, Handing Dong, Michael Berlin

Abstract

The present disclosure relates to bifunctional compounds that cause the degradation of LRRK2; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with LRRK2, including Parkinson's Disease.

CPC Classifications

C07D 413/14 A61K 31/506 A61K 31/5377 A61K 45/06 C07D 401/14 C07D 405/14 C07D 471/10

Filing Date

2023-09-06

Application No.

19109277