BENZOFURAN DERIVATIVES AS SIK INHIBITORS AND THE USE THEREOF
Application
US20260085053A1
Kind: A1
Mar 26, 2026
Assignee
BEONE MEDICINES I GMBH
Inventors
Jing Li, Fengtao Song, Zhiwei Wang
Abstract
Provided are compounds of formula (I) as well as their compositions and methods of use, wherein values for variables R1, R2, R5, X, X1, and X2 are provided herein. The compounds inhibit salt-inducible kinase activity and are useful in the treatment of various inflammatory diseases.
CPC Classifications
C07D 307/83
A61K 31/343
A61K 31/351
A61K 31/397
A61K 31/4025
A61K 31/403
A61K 31/4035
A61K 31/404
A61K 31/4155
A61K 31/4178
A61K 31/422
A61K 31/4245
A61K 31/438
A61K 31/443
A61K 31/4525
A61K 31/454
A61K 31/4709
A61K 31/4725
A61K 31/496
A61K 31/501
A61K 31/506
A61K 31/5377
A61K 31/538
A61K 31/553
C07D 405/04
C07D 405/12
C07D 405/14
C07D 407/12
C07D 413/12
C07D 413/14
C07D 471/10
C07D 491/048
Filing Date
2025-12-02
Application No.
19405502