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NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF

Application US20260085045A1 Kind: A1 Mar 26, 2026

Inventors

Jiaqiang DONG, Xinxian DENG, Wensheng YU, Fangfang JIN, Zhen GONG

Abstract

A nitrogen-containing heterocyclic derivative inhibitor, a preparation method therefor and the use thereof. Specifically disclosed are a compound as represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the compound, and the use thereof as an inhibitor in treating diseases such as cardiovascular and cerebrovascular diseases, wherein the definition of each substituent in the general formula (I) are the same as those defined in the description.

CPC Classifications

C07D 213/75 A61K 31/444 A61K 31/497 A61K 31/4985 A61K 31/501 A61K 31/506 A61K 31/517 A61K 31/519 A61K 31/52 A61K 31/53 A61K 31/541 A61K 31/55 A61K 31/551 A61K 31/553 C07D 401/12 C07D 401/14 C07D 405/14 C07D 413/14 C07D 417/14 C07D 471/04 C07D 473/32 C07D 487/04 C07D 491/048 C07D 491/052 C07D 498/14 C07D 513/04 C07D 519/00

Filing Date

2025-12-01

Application No.

19404207