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COMPOSITIONS AND METHODS FOR GENOME EDITING

Application US20260083860A1 Kind: A1 Mar 26, 2026

Inventors

Oscar ALVAREZ, Ming-Yue LEE, Blair B. MADISON

Abstract

Disclosed are methods and compositions for functional genetic modifications at selected sites. Also provided are cell populations, which comprise targeted integration of one or more exogenous polynucleotides, and/or indels at one or more selected gene loci.

CPC Classifications

A61K 48/005 A61K 9/1271 A61K 9/5123 A61P 3/06 C12N 9/226 C12N 15/111 C12N 15/88 C07K 2319/09 C07K 2319/80 C12N 2310/20

Filing Date

2025-08-19

Application No.

19303777