← USPTO Patent Applications

COMBINATION OF CAR T-CELL THERAPY WITH BTK INHIBITORS AND METHODS OF USE THEREOF

Application US20260083848A1 Kind: A1 Mar 26, 2026

Inventors

Judith A. FOX, Pietro TAVERNA

Abstract

The present disclosure provides the use of immune effector cells (e.g., T-cells or NK cells) engineered to express a Chimeric Antigen Receptor (CAR), in combination with a kinase inhibitor (e.g., a BTK inhibitor), for the treatment of a disease or disorder (e.g., a hematological malignancies).

CPC Classifications

A61K 40/4211 A61K 31/506 A61K 40/11 A61K 40/31 A61P 35/00 A61P 35/02

Filing Date

2022-11-02

Application No.

18706903