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CORTICOSTEROID CONTAINING ORALLY DISINTEGRATING TABLET COMPOSITIONS FOR EOSINOPHILIC ESOPHAGITIS

Application US20260083754A1 Kind: A1 Mar 26, 2026

Inventors

Michael A. GOSSELIN, Jin-Wang LAI, Gopi M. VENKATESH

Abstract

The present invention is directed to orally administered compositions of topically acting corticosteroids for the treatment of inflammation of the gastrointestinal tracts such as eosinophilic esophagitis. The present invention also provides a method for treating conditions associated with inflammation of the gastrointestinal tract in an individual. The method comprises administering to an individual in need thereof a pharmaceutical composition of the present invention as orally disintegrating tablets comprising a topically active corticosteroid adsorbed onto a pharmaceutically acceptable carrier such as silicified microcrystalline cellulose.

CPC Classifications

A61K 31/56 A61J 3/10 A61K 9/0056 A61K 9/2009 A61K 9/2018 A61K 9/2027 A61K 9/2054 A61K 9/2081 A61K 9/2095 A61K 45/06 B29C 43/003 B29C 43/006

Filing Date

2025-11-28

Application No.

19403674