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THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR AMYOTROPHIC LATERAL SCLEROSIS

Application US20260083723A1 Kind: A1 Mar 26, 2026

Assignee

Toray Industries, Inc.

Inventors

Mizue Ogawa, Takehiro Takahashi, Kozue Takagaki, Hiroyuki Meguro, Ken Nunettsu Asaba, Masashi Yamamoto, Marina Nogami, Riichiro Tsuji, Naoya Ukegawa

Abstract

A therapeutic or preventive agent for amyotrophic lateral sclerosis has inhibitory action against ferroptosis. The therapeutic or preventive agent for amyotrophic lateral sclerosis contains a tetrahydroquinoline derivative or a pharmaceutically acceptable salt thereof as an active ingredient. Compositions for and methods of treating amyotrophic lateral sclerosis and inhibiting ferroptosis are also disclosed.

CPC Classifications

A61K 31/4709 A61K 31/496 A61K 31/5377 A61P 25/02 A61P 25/28

Filing Date

2023-06-23

Application No.

18877122