LXR MODULATORS WITH BICYCLIC CORE MOIETY FOR TREATING DYSLIPIDEMIAS
Application
US20260083704A1
Kind: A1
Mar 26, 2026
Inventors
Archana VIJAYAKUMAR, Eisuke MURAKAMI, Claus KREMOSER, Jen-Chieh CHUANG, Steve WENG, Ryan Steven HUSS, G. Mani SUBRAMANIAN, Robert P. MYERS
Abstract
The present disclosure relates to novel compounds which are Liver X Receptor (LXR) modulators and to pharmaceutical compositions containing same. The present disclosure further relates to the use of said compounds in the prophylaxis and/or treatment of diseases which are associated with the modulation of LXR, for example, dyslipidemias. The present disclosure further relates to the use of the present compounds in the prophylaxis and/or treatment of metabolic disorders associated with an impairment in lipid homeostasis.
CPC Classifications
A61K 31/404
A61K 31/4155
A61K 31/416
A61K 31/4178
A61K 31/423
A61K 31/4245
A61K 31/427
A61K 31/437
A61K 31/439
A61K 31/4439
A61K 31/454
A61K 31/4709
A61K 31/496
A61K 31/497
A61P 1/16
A61P 3/06
Filing Date
2025-05-01
Application No.
19196617