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FORMULATIONS OF SPRAY DRIED LIPID NANOPARTICLES

Application US20260083681A1 Kind: A1 Mar 26, 2026

Inventors

Mark Kastantin, Dan Smithey, Erica Schlesinger, Ryan Mowry

Abstract

A formulation is provided for a spray dried lipid nanoparticle matrix particles, including lipid nanoparticles, a buffer system, and a barrier matrix stabilizer, wherein the barrier matrix stabilizer is included in a solid weight percent based on a maximum osmolarity and a maximum acceptable injectable volume of an injectable formulation comprising the spray dried lipid nanoparticle matrix particles.

CPC Classifications

A61K 9/5123 A61K 9/0019 A61K 9/5161 A61K 9/5192 A61K 31/7105

Filing Date

2025-09-16

Application No.

19330723