SYSTEMS AND METHODS FOR PRODUCING A BRAIN LESION FUNCTIONAL MRI BIOMARKER, PREDICTING PATIENT PROGNOSIS, AND TREATMENT PLANNING

Abstract

A system for predicting a survival outcome of a brain tumor patient includes a computing device with at least one processor and a non-volatile computer-readable media. The non-volatile computer-readable media contains instructions executable on the processor to: transform a resting-state fMRI dataset obtained from the patient into a functional connectivity matrix comprising a plurality of matrix elements, each matrix element comprising a correlation of resting-state fMRI activities of a first and second region of interest from a plurality of pre-selected regions of interest within the patient's brain, transform the functional connectivity matrix into the predicted survival outcome using a machine learning model, and output the predicted survival outcome.

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