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Materials and Methods for Treatment of Pain Related Disorders

Application US20260078414A1 Kind: A1 Mar 19, 2026

Assignee

Vertex Pharmaceuticals Incorporated

Inventors

Ante Sven Lundberg, Samarth Kulkarni, Lawrence Klein, Hari Kumar Padmanabhan

Abstract

The present application provides materials and methods for treating a patient with one or more conditions associated with SCN9A whether ex vivo or in vivo. In addition, the present application provides materials and methods for editing and/or modulating the expression of SCN9A gene in a cell by genome editing.

CPC Classifications

C12N 15/907 A61K 35/30 C07K 14/705 C12N 9/22 C12N 15/11 C12N 15/1138 C12N 2310/20 C12N 2800/80

Filing Date

2025-09-16

Application No.

19330502