Circular RNA For Translation In Eukaryotic Cells
Application
US20260078400A1
Kind: A1
Mar 19, 2026
Inventors
Daniel G. Anderson, Robert Alexander Wesselhoeft, Piotr S. Kowalski
Abstract
Circular RNA and methods and constructs for engineering circular RNA are disclosed. In some embodiments, the circular RNA includes the following elements arranged in the following sequence: a) a 3′ Group I self-splicing intron fragment, b) an internal ribosome entry site (IRES), c) a protein coding region or noncoding region, and d) a 5′ Group I self-splicing intron fragment.
CPC Classifications
C12N 15/85
C07K 16/2803
C12N 15/11
C07K 2317/31
C12N 2015/8518
C12N 2015/859
C12N 2800/107
C12N 2800/202
C12N 2800/70
C12N 2840/203
C12N 2840/55
C12N 2840/60
C12N 2999/007
Filing Date
2025-09-12
Application No.
19327522