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GENETICALLY MODIFIED MICROORGANISM, METHOD(S) AND APPLICATION(S) THEREOF

Application US20260078386A1 Kind: A1 Mar 19, 2026

Inventors

Chitranshu KUMAR, Badrish Ranjitlal SONI, Mansi Pankaj VORA, Sudip Kumar SAMANTA, Piyush SETHIA

Abstract

The present disclosure relates to genetically modified bacteria, wherein said genetically modified bacteria is designed to express or overexpress a heme-containing protein. Said protein is optionally expressed or overexpressed in combination with one or more enzymes that catalyze the heme synthesis pathway. Said genetically modified organism allows scalable production of heme-containing protein with the advantage that the expressed protein remains in soluble form without forming inclusion bodies.

CPC Classifications

C12N 15/74 C07K 14/195 C07K 14/245 C07K 14/805 C12N 9/0008 C12N 9/485 C12N 9/88 C12N 9/90 C12N 9/93 C12N 15/70 C12R 2001/19 C12Y 102/0107 C12Y 304/15006 C12Y 504/03008 C12Y 603/02029 C12Y 603/0203

Filing Date

2022-06-24

Application No.

18562620