PROBIOTICS DESIGNED TO EXPRESS AND SECRETE AKKERMANSIA MUCINIPHILA TARS, AND A VECTOR FOR PRODUCING THE SAME
Application
US20260078385A1
Kind: A1
Mar 19, 2026
Assignee
Korea Research Institute of Bioscience and Biotechnolgy
Inventors
Myung Hee KIM, Shinhye Park, Su Man Kim, Seungho Hwang
Abstract
The present invention relates to: a transformed strain expressing and secreting Akkermansia muciniphila TARS (AmTARS); and a vector for producing same. More specifically, the present invention relates to an Escherichia coli Nissle 1917 (EcN) strain expressing AmTARS, a composition comprising same, a novel vector for producing same, and an EcN transformation method using same.
CPC Classifications
C12N 15/71
A61K 9/0053
A61K 35/741
A61P 29/00
C12N 1/205
C12N 9/226
C12N 15/113
C12N 15/72
C12N 2310/20
C12R 2001/19
Filing Date
2025-11-26
Application No.
19401917