G-QUADRUPLEX-CONTAINING OLIGONUCLEOTIDES
Application
US20260078382A1
Kind: A1
Mar 19, 2026
Inventors
Stefan KIPPENBERGER, Katja STEINHORST, Jindrich CINATL, Denisa BOJKOVA, Veronika KÖNIG, Johannes KLEEMANN
Abstract
An oligonucleotide molecule has 10 to 50 nucleotides that include at least one G-quartet forming motif having 10 to 20 nucleotide residues. At least 60% of the residues of the G-quartet forming motif are guanosine or deoxyguanosine residues. The oligonucleotide molecule inhibits tumor growth and/or viral or bacterial replication and/or exerts anti-inflammatory effects in mammalian cells.
CPC Classifications
C12N 15/115
A61K 31/7125
A61P 31/14
C12N 15/1131
C12N 15/1135
C12N 2310/16
C12N 2310/313
C12N 2310/315
C12N 2310/531
Filing Date
2022-06-23
Application No.
18573718