NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF LPA IN A CELL
Application
US20260078372A1
Kind: A1
Mar 19, 2026
Inventors
David Anthony Rider, Lucas Bethge, Christian Frauendorf, Adrien Weingaertner, Judith Hauptmann, Sibylle Dames, Steffen Schubert, Stephan Tenbaum
Abstract
The present invention relates to products and compositions and their uses. In particular the invention relates to nucleic acid products that interfere with the LPA gene expression or inhibit its expression, preferably for use as treatment, prevention or reduction of risk of suffering cardiovascular disease such as coronary heart disease or aortic stenosis or stroke or any other disorder, pathology or syndrome linked to elevated levels of Lp(a) particles.
CPC Classifications
C12N 15/113
C12N 2310/14
C12N 2310/315
C12N 2310/321
C12N 2310/322
C12N 2310/344
C12N 2310/351
C12N 2310/53
C12N 2310/532
C12N 2320/30
Filing Date
2025-07-08
Application No.
19263110