Method of Inhibiting Durotaxis and/or Treating Fibrosis
Application
US20260078369A1
Kind: A1
Mar 19, 2026
Inventors
Yin Loon Lee, Brian Edmund Burke, Keng Hwee Chiam, Myeongjun Jun, Colin Stewart, Xianrong Wong, Srikala Raghavan, Avinanda Banerjee, Krystle Joy Ng
Abstract
The present invention relates to cell biology. In particular, the present invention teaches methods of contacting the cells with a LING complex inhibitor to inhibit durotaxis and, in consequence, reduce fibrosis and metastasis. Methods of treating wound healing are also disclosed herein.
CPC Classifications
C12N 15/113
A61K 38/1709
A61P 1/16
C12N 9/226
C12N 15/111
C12N 2310/14
C12N 2310/20
Filing Date
2023-09-05
Application No.
19108567