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DNA POLYMERASE-BASED GENOME EDITING SYSTEM AND METHOD

Application US20260078361A1 Kind: A1 Mar 19, 2026

Inventors

Caixia GAO, Qiupeng LIN, Guanwen LIU, Kevin T. ZHAO

Abstract

The present invention relates to the field of genetic engineering. Specifically, the present invention relates to a genome editing system and method based on DNA polymerase. More specifically, the present invention relates to a method for site-directed introduction of a target modification into a genome by combining a DNA polymerase with a sequence-specific nuclease, and at the same time providing a DNA template sequence carrying the desired modification.

CPC Classifications

C12N 9/226 C12N 9/1252 C12N 15/11 C12N 15/8213 C12Y 207/07007 C07K 2319/00 C12N 2310/20

Filing Date

2023-09-11

Application No.

19109407