Mammalian Cell Line for the Production of Modified Vaccinia Virus Ankara (MVA)
Application
US20260078353A1
Kind: A1
Mar 19, 2026
Assignee
Bavarian Nordic A/S
Inventors
Robin Steigerwald, Zhiyong Xu, Juergen Hausmann
Abstract
The present invention relates to a mammalian non-human cell line, specifically Chinese hamster ovary (CHO) cells, that is genetically modified to express poxvirus host range genes CP77, K1L and/or SPI-1 which are not expressed in MVA, and to the use of said cell line in the reproduction of MVA.
CPC Classifications
C12N 7/025
A61K 39/12
C12N 5/0682
C12N 5/10
C12N 7/04
A61K 2039/5254
C12N 2510/02
C12N 2710/24134
C12N 2710/24152
Filing Date
2023-06-30
Application No.
18879789