TREATMENT OF CANCER USING CHIMERIC ANTIGEN RECEPTOR
Application
US20260078341A1
Kind: A1
Mar 19, 2026
Inventors
Andreas Loew, Michael C. Milone, Daniel J. Powell, JR., Yangbing Zhao
Abstract
The invention provides compositions and methods for treating diseases associated with expression of a cancer associated antigen as described herein. The invention also relates to chimeric antigen receptor (CAR) specific to a cancer associated antigen as described herein, vectors encoding the same, and recombinant T cells comprising the CARs of the present invention. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises an antigen binding domain that binds to a cancer associated antigen as described herein.
CPC Classifications
C12N 5/0638
A61K 39/39
A61K 39/3955
A61K 40/11
A61K 40/31
A61K 40/36
A61K 40/4202
A61K 40/4204
A61K 40/4205
A61K 40/4211
A61K 40/4255
A61K 40/4257
A61K 40/4258
A61K 40/4276
C07K 16/28
C07K 16/2863
C07K 16/30
C07K 16/32
C12N 5/0636
A61K 2039/505
A61K 2039/55527
A61K 2239/21
A61K 2239/22
A61K 2239/31
A61K 2239/38
A61K 2239/48
A61K 2239/49
A61K 2239/58
A61K 2239/59
C07K 2317/22
C07K 2317/569
C07K 2317/622
C07K 2317/77
C07K 2317/92
C07K 2319/00
C07K 2319/03
C07K 2319/32
C12N 2510/00
Filing Date
2025-11-14
Application No.
19389401