HLA Triple Knockout Human Follicle Cells for Enhanced Hair Implantation Therapy with Integrated Biosensor System
Application
US20260078339A1
Kind: A1
Mar 19, 2026
Inventors
Reem Mahrat
Abstract
The present invention discloses a novel method for developing Human HLA-a/b/c triple knockout hair follicle stem cells (HFSCs) intended for promoting HFSCS transplantation. The method involves precise genetic modification techniques to knockout HLA-a/b/c genes, facilitating enhanced compatibility and effectiveness in hair follicles transplantation. The inventive approach aims to address challenges (donor dependent and large scar) in hair implantation therapy by leveraging advanced gene-editing and stem cell technologies.
CPC Classifications
C12N 5/0628
C12N 9/22
C12N 15/11
C12N 15/907
A61F 2/10
C12N 2310/20
Filing Date
2024-09-17
Application No.
18887146