ANTI-PTK7 ANTIBODY, AND USE THEREOF
Inventors
Seung-Taek LEE, Won-Sik SHIN, Si Won OH, So-Young CHOI, Se-Ra LEE, Sang Gil KIM
Abstract
The present invention relates to an anti-PTK7 antibody and a use thereof. The anti-PTK7 antibody according to the present invention was found to inhibit angiogenesis, as well as the growth, migration, and invasion of human umbilical vein endothelial cells (HUVECs). Additionally, it effectively suppresses tumor growth in vivo, making it a promising therapeutic agent for angiogenesis-related diseases and PTK7-positive cancers. The antibody also has potential for further development as a targeted therapy for intractable cancers, positioning it as a key global therapeutic agent. Furthermore, the antibody can be humanized for clinical applications and serve as a critical component in the development of novel therapeutics.
CPC Classifications
Filing Date
2023-09-06
Application No.
19108582