← USPTO Patent Applications

ANTI-TL1A ANTIBODY THERAPEUTIC METHODS

Application US20260078194A1 Kind: A1 Mar 19, 2026

Inventors

Sudhir PENUGONDA, Srini RAMANATHAN, Jason CHAMBERLAIN, Keith HAAN, Mayukh SUKHATME, Frank TORTI, Christopher Ricardo BANFIELD, Deepa E. CHANDRA, Mina HASSAN-ZAHRAEE, Xinli HU, Kenneth HUNG, Craig L. HYDE, Steven W. MARTIN, Srividya NEELAKANTAN, Elena PEEVA, Michael S. VINCENT, Ying WU, Zhan YE

Abstract

The present disclosure provides methods and compositions for determining the risk of a patient being non-responsive to a therapeutic dose of an anti-TNF-like ligand 1A (TL1A) antibody and methods and compositions for treating inflammatory bowel disease (IBD) with a therapeutic dose of an anti-TNF-like ligand 1A (TL1A) antibody.

CPC Classifications

C07K 16/2875 A61K 9/0019 A61K 45/06 A61P 1/00 C12Q 1/6874 C12Q 1/6883 C12Q 1/689 A61K 2039/505 A61K 2039/54 A61K 2039/545 C07K 2317/565 C12Q 2600/106 C12Q 2600/156

Filing Date

2025-11-14

Application No.

19390127