REVERSIBLE CONTROL OF CHIMERIC ANTIGEN RECEPTOR T CELLS
Application
US20260078162A1
Kind: A1
Mar 19, 2026
Inventors
Xin Zhou, DingPeng Zhang
Abstract
Disclosed are receptor traps that regulate immune cells. The receptor traps can have an ectodomain from a tumor cell that can bind to a chimeric antigen receptor (CAR) on a CAR-T cell that reversibly inhibits activation of the CAR-T cell.
CPC Classifications
C07K 14/70503
C07K 14/70578
A61K 38/00
C07K 2319/30
Filing Date
2023-09-20
Application No.
19113763