INHIBITORS FOR PROTEIN N-TERMINAL METHYLTRANSFERASE AND USES THEREOF
Application
US20260078147A1
Kind: A1
Mar 19, 2026
Inventors
Rong HUANG, Dongxing Chen, Guangping Dong
Abstract
The present invention relates to series of peptidomimetic compounds as an inhibitor targeting protein N-terminal methyltransferase pharmacological pathway. Pharmaceutical compositions of those compounds and methods of using them in the treatment of diseases caused by abnormal protein methyltransferase pathway, including cancer, inflammation, neurodegenerative and cardiovascular diseases, are within the scope of this disclosure.
CPC Classifications
C07K 7/08
C07K 7/06
A61K 38/00
A61P 9/00
A61P 25/28
A61P 29/00
A61P 35/00
C07K 5/0823
C07K 5/1024
Filing Date
2025-10-20
Application No.
19363450