COMPOSITIONS AND METHODS FOR TREHALOSE PHOSPHOLIPIDS
Application
US20260078140A1
Kind: A1
Mar 19, 2026
Inventors
Ildiko Van Rhijn, Adriaan J. Minnaard, D. Branch Moody, Tan-Yun Cheng, Jeffrey Buter
Abstract
Provided herein are compositions of trehalose phospholipids and uses thereof, e.g., compounds and compositions comprising 6,6′-diphosphatidyltrehalose (diPT) and analogs thereof with modifications of the diPT chemical scaffold, that bind and agonize Mincle, and the use thereof as adjuvants.
CPC Classifications
C07H 11/04
A61K 39/0002
A61K 39/002
A61K 39/02
A61K 39/39
A61K 45/06
C07K 16/44
C12Q 1/10
G01N 33/92
A61K 2039/55566
G01N 2405/06
Filing Date
2025-11-13
Application No.
19388195