PYRROLO-PYRIDAZINE INHIBITORS OF JAK2
Application
US20260078131A1
Kind: A1
Mar 19, 2026
Inventors
Craig E. Masse, Jiayi Xu, Phani Ghanakota, Kevin Robert DeMarco, Susanta Haldar, Alice Hooper
Abstract
The present disclosure provides pyrrolo-pyridazine compounds and compositions thereof useful for inhibiting JAK2. In some embodiments, the present disclosure provides a compound of formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, and R4 are as defined in classes and subclasses herein, both singly and in combination.
CPC Classifications
C07D 487/14
C07B 59/002
C07D 498/22
C07D 519/00
Filing Date
2025-09-05
Application No.
19320373