Process for the Preparation of Ruxolitinib and Novel Crystalline Form Thereof
Application
US20260078128A1
Kind: A1
Mar 19, 2026
Inventors
Venkata Srinivas Pullela, Sampath Kumar Upparapalli, Venkateswara Rao Kalapala, Chennakesava Reddy Bandi, Basaveswara Rao Bavireddi, Chakradhar Gadde, Prasad Ravi
Abstract
The present invention relates to an improved process for the preparation of ruxolitinib or its salts and intermediates thereof. The present invention also relates to a novel crystalline form G of ruxolitinib, a process for its preparation, use of it in the preparation of ruxolitinib salts, a pharmaceutical composition comprising it, and method of use thereof. The present invention also relates to an improved process for preparation of crystal modification 3 of ruxolitinib hydrochloride salt.
CPC Classifications
C07D 487/04
Filing Date
2025-09-23
Application No.
19336597