DEGRADER COMPOUNDS AND USES THEREOF
Application
US20260078119A1
Kind: A1
Mar 19, 2026
Inventors
Daniel K. CASHION, Jesus MORENO, David S. PETERS, Thomas J. CUMMINS, Vera PRYTKOVA, Jennifer R. RIGGS, Sophie M. PERRIN
Abstract
Provided herein are compounds and compositions thereof that reduce FAK protein levels. In some embodiments, the compounds have structures of Formula I: In some embodiments, the compounds and compositions are provided for treatment of FAK associated diseases such as cancer.
CPC Classifications
C07D 471/04
A61K 31/4545
A61K 31/496
A61K 31/501
A61K 31/506
A61K 31/519
A61K 31/5377
A61K 45/06
A61P 35/00
C07D 401/14
C07D 487/04
C07D 519/00
Filing Date
2025-03-21
Application No.
19086425