COMPOUND USED AS INHIBITOR OF CDK4 KINASE AND USE THEREOF
Application
US20260078114A1
Kind: A1
Mar 19, 2026
Inventors
Apeng LIANG, Kai WANG, Shaoqing CHEN, Jun LI, Yusheng WU, Meihua LI, Zhou YIN, Yi LONG, Chengshan NIU
Abstract
A compound used as an inhibitor of a CDK4 kinase and use thereof are provided. Specifically, the compound has a structure represented by formula (I). The definitions of each group and each substituent group are as described in the specification. The compound can be used as an inhibitor of a cyclin-dependent kinase (CDK), is used for treating or preventing proliferative diseases (such as cancer), and is in particular used for modulating and treating related diseases caused by the abnormal activity of the cyclin-dependent kinase (CDK).
CPC Classifications
C07D 413/14
A61K 31/506
A61K 31/519
A61K 31/52
A61K 31/5355
A61K 31/5377
A61K 31/538
A61K 31/542
A61P 35/00
C07D 401/14
C07D 403/04
C07D 405/12
C07D 405/14
C07D 413/04
C07D 471/04
C07D 471/10
C07D 473/32
C07D 487/04
C07D 513/04
Filing Date
2023-09-05
Application No.
19104052