IONIZABLE LIPIDS FOR NUCLEIC ACID DELIVERY
Application
US20260078085A1
Kind: A1
Mar 19, 2026
Inventors
Nikita Jain, Anitha Thomas, Andrew William Brown
Abstract
The present disclosure provides methods for modifying a cell. In one embodiment, the method includes: contacting the cell with a pharmaceutical composition including a nucleic acid payload encapsulated by a lipid mix composition having a compound of Formula (I), or a pharmaceutically acceptable salt thereof; and transfecting the nucleic acid payload into the cell.
CPC Classifications
C07C 309/69
A61K 39/00
A61K 39/001112
A61K 40/11
A61K 40/31
A61K 40/4211
C07C 219/20
C07D 205/04
C07D 207/08
C07D 453/02
Filing Date
2025-09-24
Application No.
19338244