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SYSTEMS AND METHODS FOR PRECISION DOSE DELIVERY, STERLIZATION, AND PACKAGING OF MEDICAL DEVICES

Application US20260077130A1 Kind: A1 Mar 19, 2026

Assignee

Regeneron Pharmaceuticals, Inc.

Inventors

Kenneth F. LORENZE, Dustin BLODGETT, Trevor LANGLEY

Abstract

A drug delivery device that includes a body storing a VEGF antagonist, a plunger rod contacting a stopper inside the body, and a flange coupled to the body. The body is silicone-free. The plunger rod includes protrusions and the flange includes a proximal collar and slots positioned along the proximal collar. The flange is configured such that when the protrusions and slots are misaligned, distal movement of the plunger rod relative to the body is limited upon the protrusions contacting the proximal collar to prime the drug delivery device. The flange is configured such that when the protrusions and slots are aligned, distal movement of the plunger rod relative to the body is limited upon the protrusions extending into the slots to deliver the VEGF antagonist.

CPC Classifications

A61M 5/3146 A61K 9/0019 A61K 38/179 A61M 5/31505 A61M 5/31513 A61L 2/20 A61L 2/208 A61L 2101/02 A61L 2103/05 A61L 2103/23 A61M 2210/0612

Filing Date

2025-09-17

Application No.

19331614