← USPTO Patent Applications

METHODS AND COMPOSITIONS FOR IMAGING MALIGNANCIES IN THE BONE MARROW

Application US20260077072A1 Kind: A1 Mar 19, 2026

Inventors

Monica SHOKEEN, Samuel ACHILEFU

Abstract

Compositions, methods of synthesis, and methods of use for an imaging agent that preferentially binds to activated VLA4, including, but not limited to a peptide or peptidomimetic ligand radiolabeled for use in PET imaging to identify bone marrow malignancies, help select treatments for bone marrow malignancies, and monitor relapse in bone marrow malignancy patients after therapy are disclosed.

CPC Classifications

A61K 51/088 A61P 35/00 C07B 59/008 G06T 7/0012 A61K 2123/00 G06T 2207/30008

Filing Date

2023-07-13

Application No.

18993779