UNIVERSAL NON-VIRAL GENE DELIVERY SYSTEM WITH ENHANCED STABILITY
Application
US20260077063A1
Kind: A1
Mar 19, 2026
Inventors
Tejal Desai, Kareem Ebeid, Brendan Knittle, Aliasger Salem
Abstract
The present disclosure provides, for instance, polymer-lipid hybrid nanoparticle compositions and methods of making and using them. The polymer-lipid hybrid nanoparticle may comprise, for example, poly(lactic-co-glycolic) acid (PLGA), polyethylenimine (PEI), and D-Lin-MC3-DMA (MC3). The polymer-lipid hybrid nanoparticle can be used to deliver, for example, nucleic acids and small molecules, cells.
CPC Classifications
A61K 48/0058
A61K 47/593
A61K 47/595
A61K 48/0041
C12N 15/88
Filing Date
2025-09-18
Application No.
19332428